Prolonged endotracheal intubation is associated with a lot of complications including ventilator related pneumonia, airway damage, or threat of reintubation. Reintubation is a selected downside particularly because of the lack to cooperate with peri-extubation maneuvers, and the relatively high sedation requirements. Children who have extreme thirst might have excessive blood sugar ranges. In conclusion, a number of studies have recommended that prophylactic NIV could scale back the danger of post-extubation respiratory failure in ICU patients at high threat of extubation failure. Further research are wanted to elucidate the efficacy of HFNC during weaning from prolonged mechanical ventilation in a larger inhabitants to forestall submit-extubation respiratory failure in patients at high threat of extubation failure within the intensive care unit and such a clinical situation where NIV is just not beneficial. 106 mm Hg), as a way to keep away from tracheostomy on ICU day sixteen the first weaning try was made. We recommend that the primary setting of HFNC move be the identical as the utmost inspiratory move of the ventilator during pressure assist ventilation, and the duration of HFNC be progressively prolonged together with physiotherapy rehabilitation. It is vital, nevertheless, that you talk about this together with your personal physician and first acquire acceptable lab exams